Personalized Neoantigen Cancer Vaccines| A New Breakthrough
The introduction of the neoantigen cancer vaccines is an obvious example of developing oncology care that has the potential to overcome the present obstacles of treatment non-specificity and safety criteria. Neoantigens are foreign peptides that are totally absent from normal healthy cells and are particularly recognized by neoantigen-specific T-cell receptors in terms of current histocompatibility complexes (MHCs) molecules. Unlike tumor-associated antigens and cancer germline antigens, which are generally found on both cancer and healthy cells, neoantigens are only found in tumor tissues. What is Neoantigen? Gene mutations generated by genetic…
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